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Primary Antibodies  >  Cytokines & Growth Factor Antibodies
 

IL-17E Antibody

Mouse Monoclonal 11K8B1 IgG1
Code

209-301-C58
Size

100 µg
Price

$309.00
Availability

Ships next business day.
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Phone: 800.656.7625
E-mail: orders@rockland-inc.com
Fax: 610.367.7825
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Flow Cytometry of Mouse anti-IL-17E antibody  
Cells:  PC3 cells
Primary antibody:  1 ug of IL-17E (red), control (green)
Secondary antibody: anti-mouse IgG PE conjugated secondary antibody.
Western Blot of Mouse anti-IL-17E antibody  
in full  length recombinant protein using IL-17E antibody at 0.5 ug/ml.
Shipping & Handling Fees Apply.

Shipping:
$85.00 to United States
Handling:
$20.00
Synonyms: Interleukin 25, IL-25, Interleukin 17E, IL-17E

IL-17E Antibody Properties

Description
Anti-Human IL-17E (MOUSE) Monoclonal Antibody - 209-301-C58
Host
Mouse
Target Species
Human
Known Cross Reactivity
human
Clonality
Monoclonal 11K8B1 IgG1
Application
ELISA : 1:10,000-1:50,000
FlowCytometry : 1µg/mL
Western Blot : 0.5µg/mL
Other Dilution: User Optimized
Physical State
Liquid (sterile filtered)
Shipping condition
Dry Ice
Format
IgG1
Label
Concentration
1.0 mg/mL by UV absorbance at 280 nm
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
0.01% (w/v) Sodium Azide
Stabilizer
None
GeneName
IL25
Download CofA
Lot#  

IL-17E Antibody Description

Background
Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.
Immunogen
Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
Immunogen Type
Recombinant Protein
Storage Condition
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Application Note
IL 17E antibody has been tested for use in Flow Cytometry and western blotting. Specific conditions for reactivity should be optimized by the end user.
Purity/Specifity
Anti-IL-17E was purified from concentrated tissure culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-17E protein. A BLAST analysis was used to suggest cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17E from other sources has not been determined.
Disclaimer Note-General
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 326, Gilbertsville, Pennsylvania, USA.
General Reference
Basso AS, Cheroutre H, Mucida D. (2009) More stories on Th17 cells. Cell Research 19:399–411. doi: 10.1038/cr.2009.26; published online 3 March 2009. Conti HR, Shen F,Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hoda Hai J, Yu JJ, Won Jung J, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL. (2009) Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. February 16; 206(2): 299–311. doi: 10.1084/jem.20081463. Lee J. (2001) IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. et al. Journal of Biological Chemistry. Xu S., Cao X. (2010) Interleukin-17 and its expanding biological functions. Cellular & Molecular Immunology. Korn T. (2009) IL-17 and Th17 Cells. et al. Annual Review of Immunology.
Specific Reference
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Product Type
Primary Antibodies;
Applications
ELISA, WB, FC
Reacts With
Human
Catalog Number
209-301-310

Product Type
Primary Antibodies;
Applications
ELISA, WB, IHC
Reacts With
human
Catalog Number
209-301-B31

Product Type
Primary Antibodies;
Applications
ELISA, WB, FC
Reacts With
human
Catalog Number
209-301-B32

Product Type
Primary Antibodies;
Applications
ELISA, WB
Reacts With
human
Catalog Number
209-301-B61

Product Label

 

Description
Unconjugated
Color
Conjugation Reference
Molecular Weight
Excitation Wavelength
Conjugation Chemistry