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Datasheet

Avian Influenza Hemagglutinin 4 Antibody

Goat Polyclonal

600-101-G79
100 µg
ELISA
Virus
Goat
$475.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

Anti-Avian Influenza Hemmagglutinin 4 antibody detects the internal portion of Hemagglutinin protein. Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. Anti-Avian Influenza Hemmagglutinin 4 antibodies are ideal for investigators involved in infectious disease research.

Product Details

Anti-Avian Influenza Hemagglutinin 4 (GOAT) Antibody - 600-101-G79
Avian Influenza Hemagglutinin 4, AFHA-4, Avian flu hemagglutinin, Avian influenza H5
Goat
Polyclonal
IgG

Target Details

HA  - View All HA Products
Virus
Conjugated Peptide
Avian Influenza Hemmagglutinin 4 Antibody was produced from whole goat serum prepared by repeated immunizations with a synthetic peptide corresponding to an internal region of the Hemagglutinin protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
Anti-Avian Influenza Hemmagglutinin 4 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Avian Influenza Hemmagglutinin 4 with virus based on 100% homology with the immunizing sequence. Cross-reactivity with Avian Influenza Hemmagglutinin 4 from other sources has not been determined.

Application Details

ELISA
Anti-Avian Influenza Hemagglutinin Antibody is tested for use in ELISA. Expect a band approximately ~64.2 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Formulation

Liquid (sterile filtered)
1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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