Rockland Immunochemicals was a proud sponsor of The Scientist's Spotlight on Epigenetics Drug Discovery. This webinar brings together a panel of experts to address some of the key questions that the field of epigenetics is grappling with today.Speakers:MARGARET PORTER-SCOTT, PhD, Senior Director, Lead Discovery, Epizyme Inc.JATINDER SINGH, PhD, Principal Scientist, Drug Safety and Metabolism, AstraZeneca Pharmaceuticals
To support epigenetic research and our Epi-Plus antibodies, Rockland offers a comprehensive group of peptides to provide a one stop shop for epigenetic researchers.
Epigenetics (“above” genetics) is the study of DNA, RNA and protein modifications that do not involve changes in gene sequences. The modifications involve the acetylation and/or methylation of DNA or protein and are referred to as “Epigenetic marks”. These marks, studied primarily in histones and other proteins that control the regulation of gene expression, transcription, and protein-protein interaction, have been implicated in an array of human pathophysiological conditions that includes cancer, obesity, diabetes, drug addiction (and addictive phenotypes in general), and post-traumatic stress disorder. The pattern of Epigenetic marks on histones coordinate the binding of repressors, activators, and other proteins. Current research is focused on understanding how specific patterns of marks can act in a coordinated fashion to generate a specific phenotype.
At Rockland, we have produced antibodies specifically for epigenetics that are unique to the research community. These antibodies are multi-assay validated prior to release and are validated for performance in multiple species. But there is more to this story. The quality of our starting reagents, the proper controls during antibody manufacture and the proper quality control testing prior to release are all part of this success story. Find out more about Rockland’s superior antibodies for epigenetics research. Compromise elsewhere.
View the Rockland & Leica HDAC Poster
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the modified histone map poster
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