Jagged 2 antibdody detect the Jagged protein. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. Anti-Jagged 2 antibody is ideal for investigators involved in developmental biology research.
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Anti-Jagged-2 [RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged-2. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. Swiss Prot accession Q9QYE5. Expected to cross-react with rat Jagged-2.