Proteins and Peptides  >  Control Peptides
 

IKKß Peptide

NCI Collaboration JCYIA Product
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Number:
100-401-220p
Size:
50 µg
Price:
$104.00
Shipping:
$41.00
Handling:
$20.00
Availability:
Ships next business day.

IKKß Peptide Properties

Description
IKKß Peptide - 100-401-220p
Application
Other Dilution: Control peptide should be used at 1.0 µg per 1.0 µl of antiserum per assay. 
Species of Origin
Human
Physical State
Liquid (sterile filtered)
Shipping Condition
Dry Ice
PSC Type
Synthetic Peptide
PSC Format
Peptide
Label
Concentration
1.0 mg/mL by dry weight
Buffer
None
Preservative
0.01% (w/v) Sodium Azide
Stabilizer
None
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IKKß Peptide Description

Background
Intended for use as a control peptide when used with anti-IKKB to block specific interaction of anti-IKKB [p/n 100-401-220]. NFkB comprises a family of cellular transcription factors that are involved in the inducible expression of a variety of cellular genes that regulate the inflammatory response and control of cell death. In the cytoplasm NFkB is negatively modulated by the inhibitory proteins IkB. In turn IkB is phosphorylated by a cellular kinase complex called IKK. IKK is a heterodimer composed of two kinases: IKK-a and IKK-b that phosphorylate IkB leading to its degradation and the resulting translocation of NFkB to the nucleus. IKK kinase activity is modulated negatively by pharmaceutical agents such as aspirin and positively by various cellular components such as TNF- a, endotoxins and overexpression of cellular kinases like MEKK1. Aspirin appears to have its effect by inhibiting the binding of ATP to IKK.
Synonyms
IKKB, I-kappa-B-kinase beta, IKK-B antibody, IKK-beta, IkBKB, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB, IKK2, control peptide, blocking peptide
Storage Condition
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Application Note
Control peptide should be used at 1.0 µg per 1.0 µl of antiserum in per assay.
Purity/Specifity
Greater than 95% specific peptide
Disclaimer Note-General
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
General Reference
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Product Type
Primary Antibodies;
Applications
ELISA, WB
Reacts With
human, mouse, rat
Catalog Number
100-401-219

Product Type
Proteins and Peptides;
Catalog Number
100-401-219p

Product Type
Proteins and Peptides;
Catalog Number
100-401-220p

Product Type
Primary Antibodies;
Applications
ELISA, WB, IHC
Reacts With
human
Catalog Number
100-401-264

Product Label

 

Description
Unconjugated
Color
Conjugation Reference
Molecular Weight
Excitation Wavelength
Conjugation Chemistry