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Datasheet

Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugated

Rabbit Polyclonal

200-403-046 200-403-046S 200-403-046-0100
20 mg 25 µL 100 µg
ELISA, Dot Blot
Human
Rabbit
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$125.00 /Per Item
$455.00 /Per Item
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Background

Alpha-1-Acid Glycoprotein Antibody detects alpha-1-acid glycoprotein (AGP or AAG. ) Alpha-1-acid glycoprotein is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein).[1] Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV. The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels; if anything, there is a small increase in α1 acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. Anti-Alpha-1-Acid Glycoprotein Antibody is ideal for investigators involved in infectious disease and cell cycle protein research.

Product Details

Anti-Alpha-1-Acid Glycoprotein (RABBIT) Antibody Peroxidase Conjugated (BULK ORDER) - 200-403-046
rabbit anti-Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugation, HRP conjugated rabbit anti-Alpha-1-Acid Glycoprotein 1 Antibody, AGP1, AGP 1, OMD 1, OMD1, Orosomucoid-1
Rabbit
Peroxidase (HRP)
Polyclonal
IgG

Target Details

ORM1  - View All ORM1 Products
Human
Native Protein
a-1-Acid Glycoprotein [Human Plasma]
Anti-Alpha-1-Acid Glycoprotein Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified a-1-Acid Glycoprotein [Human Plasma].  Cross reactivity against a-1-Acid Glycoprotein from other sources is unknown.

Application Details

Dot Blot, ELISA
Anti-Alpha-1-Acid Glycoprotein peroxidase Antibody has been tested by ELISA and dot blot and is suitable for Western Blot and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.

Formulation

Lyophilized
10 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide!
10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
2.0 mL
Restore with deionized water (or equivalent)

Shipping & Handling

Ambient
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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