Neuroscience Related Antibodies


Neuroscience Overview

 

Neuroscience focuses on the study of the nervous system and its structural and functional organization. It incorporates several scientific disciplines that approach different aspects of the nervous system including cellular and molecular biology, development, physiology, evolution and behavioral science among others. 

 

Recent reports from the World HealthOrganization (WHO) shows that different types of neurological disorders can affect up to one billion people worldwide. Common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, Parkinson’s disease, stroke and traumatic brain injuries are now considered very important public health problems that affect both developed and developing countries. Elucidating the nature of these pathologies and how to manage and treat them properly has been critical in propelling neuroscience research globally. An important aspect of such research is the identification and characterization of key molecules that can be used as biomarkers for both the assessment of patients at risk of neurological disorders and also as targets for novel therapeutic approaches.

 

The study of the nervous system includes multiple signaling pathways involving the Beta-amyloid isomers Aß40 and Aß42 metabolism, oxidative stress, blood barrier, dopamine signaling, and gamma-aminobutyric acid (GABA) interactions among many others. Rockland also has available antibodies specific to research involving the underlying causes in the onset and progression of neurodegenerative disorders like Alzheimer's disease. Included in Rockland's portfolio of antibodies are probes specific to Beta-amyloid isomers Aß40 and Aß42, as well as an array of full-length and truncated isomer-specific peptides displaying characterized mutations.  



Antibodies for Neuroscience

 

Neurological research relies heavily on antibodies that can help identify and elucidate reactions on the cellular, molecular and biochemical level, which may lead to a better understanding of a variety of neuroscience processes and neuronal diseases. Antibody-based approaches for isolation, characterization and localization of target proteins are among the most critical and widely used techniques in molecular and cellular neuroscience, leading to rapid development in our knowledge of protein abundance, distribution, structure, and function. Rockland’s neuroscience antibodies exhibit high specificity, selectivity and reproducibility by Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) and ELISA. These antibodies are routinely used for characterization of neural development, stem cell and differentiation, neural transmission, neurodegenerative disease and neuroinflammation.




Featured Rockland Antibodies for Neuroscience

 

600-401-417   200-342-269   200-901-D60-GF
   

 

 

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Immunoassays for Neuroscience

 

With demonstrated experience in development and validation of multiple assay formats, Rockland scientists continuously deliver optimized immunoassays for neuroscience. In particular, ELISA kits provide a valuable, efficient solution for determination of critical targets involved in neural development, synaptic signaling and neurodegeneration. Rockland’s AccuSignal ELISA Kits guarantee high precision, accuracy, sensitivity, and specificity. Each neuroscience ELISA kit is optimized for accurate quantitation of targets in various sample types, including serum, plasma, saliva, cell lysates, and/or cell culture supernatants. Additionally, cell viability assays further complement a broad suite of tools for deep characterization of neuronal signaling pathways. 

 


 

Featured Immunoassays for Neuroscience

 

Product   Catalog #    Size  
Human NGF/NGF beta AccuSignal ELISA Kit   KOA0276   1 Kit
         
Mouse GDNF AccuSignal ELISA Kit   KOA0570   1 Kit
         
Human NRCAM AccuSignal ELISA Kit   KOA0851   1 Kit
         
Rat Neuropilin-2 AccuSignal ELISA Kit   KOA0810   1 Kit
         
Human COMT AccuSignal ELISA Kit   KOA0849   1 Kit

 



Proteins and Peptides for Neuroscience

 

Rockland offers a wide range of neuroscience recombinant proteins and peptides from human, mouse and other species that can be used in a variety of assays as controls or for other purposes since they exhibit a 90% purity. Alternatively, scientists can also take advantage of Rockland’s Custom Services for reliable generation of tailored proteins and antibodies among others.

 

 

Product   Catalog #    Size  
MYT1 recombinant protein-GST fusion protein   009-001-S53   50 µg
         
UBE2K(UBC1) recombinant protein-HIS Epitope   009-001-U39S   20 µg
         
Beta Amyloid 11-40 peptide   000-001-L18   1 mg
         
Beta Amyloid 40, Biotin Conjugated peptide   000-006-K96   0.5 mg

  

 

 
   Cover Page 

Click here to download the 2017 Neuroscience Antibodies brochure 



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